Understanding BAG3-Associated DCM: From Genetics to Research Opportunities
Date: Monday, November 16, 2026
Time: 6:00pm EDT
What makes BAG3-associated dilated cardiomyopathy (DCM) different from other genetic forms of heart muscle disease, and what should patients and families know about current research?
Join Neal Lakdawala, MD, and Jonathan Lu, MD, PhD, for a patient-friendly discussion of BAG3-associated DCM, clinical research, and ways to find support.
Topics will include:
- Understanding BAG3-associated DCM and how it may differ from other genetic forms of DCM
- Exploring Alexion’s DCM Restore Study and the ALXN2350 investigational therapy, including how it is intended to work.
- Understanding what study participation may involve after informed consent, including the time commitment.
- Talking with your doctor about this and other research opportunities that may be relevant to you.
The webinar will conclude with a live Q&A.
Featured Speakers
Neal K. Lakdawala, MD, MSc, FAHA
Assistant Professor of Medicine, Harvard Medical School; Director, Fellowship in Advanced Heart Failure and Transplantation, Brigham and Women’s Hospital.
Dr. Lakdawala is a cardiovascular genetics specialist whose research focuses on understanding how genetic cardiomyopathies develop and progress, including BAG3-associated DCM, and advancing clinical trials in this evolving field.
Jonathan Lu, MD, PhD
Executive Medical Director, Clinical Development, Rare Cardiology, Alexion Pharmaceuticals. Dr. Lu is a cardiologist whose academic practice included cardiovascular genetics and electrophysiology at Columbia University Medical Center. He now focuses on developing cardiovascular precision therapeutics, including gene therapy.